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Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but They may be unusual In this particular malignancy in comparison to other lymphoid neoplasms. CHD2 is mutated in 5% of CLL and 7% of MBL.75 The histone methyltransferase SETD2 and ARID1A can also be mutated in a small proportion of people. Of Notice, MYD